What is low dose naltrexone?

Low dose naltrexone (LDN) is an adjusted form of the medication naltrexone, originally used to treat opioid addiction by blocking opioid receptors. At low doses, typically ranging from 1 mg to 4.5 mg, it produces a different therapeutic effect.

Key points include:

1. Mechanism: LDN temporarily blocks opioid receptors, prompting the body to increase production of endorphins, which helps modulate the immune system and reduce inflammation 1 2.

2. Applications: It's used for autoimmune diseases like multiple sclerosis and rheumatoid arthritis, highlighting its role in modulating immune responses 2 1. There's also growing use in conditions with immune dysregulation, such as autism 2.

3. Fibromyalgia: LDN has shown promise in treating fibromyalgia due to its ability to block specific receptors related to pain pathways, thus providing relief from chronic pain 3.

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     Low Dose Naltrexone

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     2

     Brain Health Strategies

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     3

     Understanding Fibromyalgia

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4. Safety: Considered very safe with minimal side effects, it is noted for its low toxicity and well-tolerated nature. However, potential side effects include sleep disturbances, but these are generally mild and not widespread 2 1.

The multifaceted benefits and minimal risks make LDN a compelling option for various chronic conditions, emphasizing its broader potential beyond initial uses in addiction treatment.