How much TRT to take

The recommended dosage for testosterone replacement therapy (TRT) varies based on individual health factors, but general guidance from discussions with Andrew Huberman and Kyle Gillett on the Huberman Lab include:

1. Dosage: Typically, the dosage ranges from 100 to 120 milligrams per week. This can be divided into smaller doses administered two to three times per week to maintain stable levels and minimize spikes and troughs 1.

2. Administration: The preferable method for many is through injections because they provide more stable levels and minimize the side effects associated with fluctuations in testosterone levels. Other methods like topical applications or capsules (testosterone undecanoate) are available but usually depend on specific patient needs and how well they tolerate these methods 1.

3. Considerations: It's important to note that the typical dosages aim for a physiological range, and exceeding this can lead to various health risks, including changes in mood, skin issues, and cardiovascular effects. Continuous monitoring by a medical professional is advised to adjust dosages and ensure safety 2.

Always consult a healthcare provider for personalized advice, as they can guide the most suitable TRT plan based on one's health condition and testosterone levels.