Phosphadylserine

Andrew Huberman has discussed phosphatidylserine several times in his podcast, emphasizing its role in supporting brain and cognitive function. Here are some key insights:

1. Cognitive Function and Brain Health: Phosphatidylserine is known for supporting neuronal function and improving cognition. It is abundant in meats and fish, and can also be supplemented. Supplements are available typically at 300 milligrams per day, and have been shown to improve cognition and reduce cognitive decline in several studies 1.

2. ADHD: For children with ADHD, studies suggest that taking 200 milligrams of phosphatidylserine daily for two months can reduce symptoms. This effect appears to be enhanced when combined with omega-3 fatty acids 2.

3. Cortisol Management: Phosphatidylserine is also mentioned as a component in some supplements used to manage cortisol levels, alongside ashwagandha. It's suggested to be useful for reducing high cortisol levels, particularly when they occur at night 3.

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     1

     Brain-Boosting Foods

     00:20:35
     
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     2

     Omega-3 Insights

     01:48:04
     
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     3

     Adaptogens and Cortisol

     01:39:11
     
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     4

     Brain-Boosting Nutrients

     00:47:27
     
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     5

     Brain Function Essentials

     00:28:25
     

4. Supplementation versus Diet: While phosphatidylserine can be supplemented, Dr. Huberman highlights that it's possible to obtain sufficient levels from diet, particularly if you consume enough fish and meat. However, for those who don't enjoy these foods, supplementation could help reach beneficial levels 4.

5. Overall Brain Support: Alongside other nutrients like omega-3 fatty acids and choline, phosphatidylserine is recommended to support brain function and cognitive health in both the short and long term 5.

These insights provide a comprehensive view of phosphatidylserine's potential benefits and how it can be incorporated into a diet or supplement regimen for improved cognitive health.