Overmethylation

Overmethylation is a term often associated with an excess of methylation activity in the body. Here are some key points and insights from trusted experts on the topic of overmethylation:

1. Neurotransmitter Imbalances: Overmethylation can result in high levels of neurotransmitters in the brain, such as dopamine, norepinephrine, histamine, and glutamate. This can lead to a hyperactive fight or flight response and impacts behaviors and mood 1.

2. Methylation Priority Principle: According to Dr. Daniel Pompa, stress (physical, chemical, emotional) consumes methyl groups, which are crucial for activating and deactivating stress responses. This prioritization can lead to depleted methylation resources when they are needed for other crucial functions like detoxifying hormones and protecting DNA 2.

3. General Methylation Discussion: Gary Brecka emphasizes methylation's critical role in human optimization and health. He suggests that many common ailments attributed to aging or environment might actually be due to methylation imbalances or nutrient deficiencies, impacting everything from mental health to physical symptoms like poor sleep and digestion 3.

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     Neurotransmitter Imbalance

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     2

     Methylation Priority Principle

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     3

     Methylation Matters

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Understanding and managing methylation levels can be crucial for maintaining balanced biochemical reactions in the body and avoiding the detrimental effects of overmethylation.