What is curcumin and its effects?

Curcumin, a compound found in turmeric, has several notable effects and uses, particularly as an anti-inflammatory agent and migraine treatment. Notably, curcumin can affect hormonal pathways by being a potent inhibitor of dihydrotestosterone (DHT), which plays roles in libido, beard growth, and other bodily functions. However, its impact on DHT can lead to undesirable effects like reduced libido in sensitive individuals. Dosages for curcumin can vary, with some studies examining doses as low as 80 milligrams per day which, when taken with omega-3 fatty acids, have shown effectiveness in reducing migraine frequency and intensity.

However, curcumin is also known to inhibit the enzyme cytochrome P450, which is important for blood coagulation, prompting caution for individuals on anticoagulant medications. Curcumin usage should always be discussed with a healthcare provider, especially due to its impactful effects on hormonal and enzymatic pathways 1 2.