Signaling Dynamics
The stability of signaling molecules directly influences how quickly a response is felt, with rapid actions needed for processes like swelling and blood clotting. Conversely, developmental processes can afford to take longer, utilizing more stable signaling molecules. Additionally, the effects of signals can vary from permanent changes, such as apoptosis, to temporary desensitization, which can lead to drug tolerance as cells adapt to constant signaling.In this clip
From this podcast
The Science of Everything Podcast
Episode 118: Cell Signalling
Related Questions
So receptors don't get damaged but are just desensitized, right or wrong?
Is it possible to help the body regenerate specific receptors that may have become internalized or underproduced, allowing patients who have become overtly tolerant to use less medication at a lower dose while still producing the same symptomatic response?
Can dopamine receptors downregulate or become desensitized immediately after intense dopamine spikes, such as those caused by high-intensity activities, even for a short duration?