Brain and Depression

The corticolimbic system, which includes the amygdala and hippocampus, plays a crucial role in processing emotions and memories. Antidepressants may enhance neural plasticity in these regions, addressing the dysregulation seen in depression. Additionally, cognitive distortions, such as selective abstraction, can exacerbate depressive symptoms by focusing on negative aspects of situations, highlighting the complex interplay between brain function and emotional well-being.