The discussion reveals that all statins, regardless of their hydrophilic or lipophilic nature, can cross the blood-brain barrier, debunking common myths about brain fog associated with specific statins. While side effects like muscle aches and potential insulin resistance are noted, the choice of statin should primarily focus on its ability to lower APOB and any drug interactions. Pitavastatin stands out as the only statin without a predisposition to diabetes, yet it remains underutilized in practice.
