Antibody Dependent Enhancement

Erin and Maria delve into the concept of antibody dependent enhancement (ADE), explaining its implications for vaccine efficacy, particularly in the context of dengue. They highlight that while ADE is a concern, studies show that neutralizing antibodies from COVID vaccines like Pfizer and Moderna offer protection against severe disease. The favorable safety profiles observed in clinical trials further bolster confidence in these vaccines, despite ongoing assessments of ADE risks.