High School Hangovers

I have a question about the episode #652 Grief - Marc Maron and the clip Love and Sobriety. I struggle with addiction; I start drinking or using drugs, and it gets bad quickly, with 3-day hangovers and week-long withdrawals. I’ll get sober, but a week or two later, I relapse. Sometimes it's worse than others, depending on how fast I decide I need to stop. I’m severely depressed and tired of living like this. I get no joy or tranquility, which makes me give in to drinking and drugs again. I desperately want to be sober and find peace. Is there anything specific I can focus on, such as vitamins, gut health, or other lifestyle changes, to break this vicious cycle?