Nicotinamide Insights
Nampt plays a crucial role in regulating health by recycling nicotinamide to NAD+, which is essential for sirtuin activity. A surprising finding reveals that nicotinamide may inhibit sirtuins, acting as a feedback regulator that could hinder their function. This discovery emerged from early experiments demonstrating that high levels of nicotinamide resulted in inactive sirtuins, reshaping our understanding of its impact on cellular processes.In this clip
From this podcast
Paul Saladino MD podcast
19. Can we live forever? A conversation about aging with David Sinclair PhD
Related Questions
How does NAD relate to sirtuins in the context of the episode Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More and the clip NAD and Resveratrol?
How does NAD relate to sirtuins in the context of the episode 170: Why aging may be a disease we can reverse, with microbiologist David Sinclair, Ph.D. and the clip Understanding NAD and Sirtuins?
What's the deal with nicotinamide?