Valter Longo discusses the concept of metabolic set points and how they contribute to weight management. He explains that our bodies have a natural "safe" weight that they strive to maintain, and that obesity may actually be a survival mechanism. Rather than stigmatizing obesity, Longo suggests focusing on helping individuals achieve a weight that makes them happier and healthier. Rich Roll explores the possibility of changing metabolic set points to create a new, healthier steady state.