207: Life lessons from a doctor who almost died from an incurable disease | David Fajgenbaum, M.D.

Diagnosis

David Fajgenbaum was a thriving medical student when he began experiencing severe fatigue and other alarming symptoms. His condition rapidly deteriorated, leading to a shocking diagnosis of Castleman disease. He recalls the terrifying experience of being hospitalized and receiving his last rites at just 25 years old.

I was so sick that back in November of 2010, the doctors didn't think I would survive. My family came to say their goodbyes to me, and a priest came in and administered my last rites.

--- David Fajgenbaum

Despite the grim prognosis, chemotherapy saved his life, though he faced multiple relapses 1 2.

   

Finding Cure

Determined to find a cure, David immersed himself in Castleman disease research. He conducted experiments on his own samples and discovered that a 30-year-old drug, sirolimus, might work. His relentless pursuit paid off, leading to a significant remission.

I started taking this drug called sirolimus, and it's now been over six years that I've been in remission.

--- David Fajgenbaum

This breakthrough not only saved his life but also offered hope to other patients 3.

   

Athletic Background

David's background as a college athlete played a crucial role in his resilience. The physical and mental toughness he developed through sports helped him endure the grueling treatments and hospitalizations. He believes that his athletic training prepared him for the intense challenges of battling a life-threatening illness.

I think that sports and training like that can actually prepare you in some ways for it.

--- David Fajgenbaum

His experience underscores the importance of physical fitness and mental fortitude in overcoming adversity 1 4.

   

Faith & Action

Faith played a significant role in David's journey, evolving from passive hope to active pursuit of a cure. Inspired by a quote from Pope John Paul, he realized that faith should drive action. This shift in mindset propelled him to take control of his treatment and research.

Pray, hope, and take action.

--- David Fajgenbaum

His story highlights the power of combining faith with proactive efforts to overcome seemingly insurmountable challenges 5.