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  • Inositol

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    Inositol, particularly in the form of myo-inositol, has been explored and discussed extensively by for its various health benefits. Here are some of the key insights from on inositol:

    Anxiety and PTSD

    1. Dosage: High dosages (12-18 grams) of inositol are used to improve symptoms of anxiety and may indirectly support those working through trauma and PTSD. However, these high dosages demand caution due to possible side effects like gastric discomfort 1.
    2. Application: Inositol may not be advisable during sessions intending to amplify the intensity of traumatic experiences for therapeutic purposes because it could interfere with the process of extinguishing those experiences 1.

    Sleep and Mental Health

    1. Sleep Quality: personally uses 900 mg of myo-inositol to enhance the depth and quality of his sleep, often combining it with other supplements like magnesium threonate, apigenin, and theanine. He reports that this leads to enhanced focus and alertness during the day 2 3.
    2. OCD and Other Uses: Inositol has been used at very high dosages (5-18 grams) to mitigate symptoms of OCD and has been shown to possess qualities that could reduce migraine symptoms and assist in conditions like ADHD and bipolar disorder 3.

    Cellular Mechanisms

    1. Cell Signaling: Inositol is linked to second messenger pathways, influencing cell membrane fluidity and potentially impacting gene expression. It plays a significant role in the cellular processes vital for maintaining various physiological functions 4.

    Fertility

    1. Insulin Sensitivity and Reproductive Health: It is suggested, especially for individuals facing fertility issues, that myo-inositol can improve egg and sperm quality due to its effects on insulin sensitivity. Dosages recommended for this purpose range between 1 to 5 grams per day 5.

    While inositol exhibits potential health benefits, especially at high dosages, it's essential to consult healthcare professionals before starting or modifying supplement intake due to its potent effects and possible side effects.

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