• Fasting mimicking diet details and routine by Valter Longo & Peter Attia

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    The fasting mimicking diet (FMD), pioneered by , aims to capture the benefits of traditional fasting without requiring a complete absence of food. This diet typically involves a low-calorie, low-protein, low-sugar regimen over a period of days and is designed to mimic the effects of fasting by impacting key biomarkers such as IGF-1 and glucose levels. The typical FMD protocol involves consuming around 1,100 calories on the first day and 800 calories on the subsequent days, over a total of five days. This approach is intended to simulate the physiological effects of water-only fasting without the associated risks like hypotension or hypoglycemia 1.

    discusses various fasting regimens, noting that the FMD developed by typically involves a 75% reduction in calorie intake over five days, and is recommended every few months. Attia emphasizes that there are numerous fasting regimens available, and finding the right one depends on individual goals and health outcomes 2. He also discusses the importance of adjusting fasting protocols based on specific health situations, ensuring they align with desired health benefits 3.

    suggests that for most people, undergoing the FMD two to four times a year might be sufficient, but this can vary based on individual needs and health conditions. Currently, there are numerous clinical trials underway to further understand its effectiveness and safety in various populations 1.

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