Published Jul 19, 2023

The Truth About Ketones: Benefits & Impact on Brain Health w/ Dr. Latt Mansor | 260 | Kelly LeVeque

    Dr. Latt Mansor and Kelly LeVeque delve into the transformative power of exogenous ketones on brain health, metabolism, and energy, revealing their potential to enhance cognition, mood, and athletic performance while offering therapeutic benefits for brain injuries and diseases.
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    • Brain Fuel

      Ketones serve as a powerful alternative fuel source for the brain, enhancing metabolism and reducing inflammation. Dr. Latt Mansor explains that ketones can fill the energy gap in the brain, especially when glucose metabolism is impaired, such as in traumatic brain injuries or neurodegenerative diseases 1. This alternative energy source not only supports brain function but also offers anti-inflammatory benefits, which are crucial for long-term brain health 2.

      Ketones essentially fuel human beings and a lot of other organisms when they are fasted for the brain.

      --- Dr. Latt Mansor

      Kelly LeVeque highlights the importance of metabolic flexibility, emphasizing how ketones can aid in preventing conditions like Alzheimer's, often referred to as type three diabetes 3.

         

      Therapeutics

      Research into ketones reveals promising therapeutic applications for brain-related injuries and diseases. Dr. Mansor discusses how ketones bypass glucose transporters, providing an alternative energy source for the brain through monocarboxylase transporters 4. This mechanism is particularly beneficial in cases where glucose metabolism is impaired, such as in traumatic brain injuries and neurodegenerative diseases 5.

      You are providing a separate tank of fuel that the brain can have access to.

      --- Dr. Latt Mansor

      Kelly shares her personal experience with ketones during pregnancy and postpartum, noting their role in maintaining energy levels and supporting brain health 6.

         

      Cognition

      Ketones play a significant role in enhancing cognition and mood, offering potential benefits for mood disorders like depression and anxiety. Kelly notes that ketones, combined with a whole food diet and proper hydration, can help manage postpartum energy depletion and stress 7. Dr. Mansor adds that ketones may improve symptoms of major depressive disorders by balancing stress hormones and increasing brain-derived neurotrophic factor (BDNF) 7.

      It helps you, it gives you energy, it gives you the mental clarity.

      --- Dr. Latt Mansor

      Kelly emphasizes the cognitive benefits she experiences from ketones, which help her maintain focus and energy throughout her demanding schedule 8.

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